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Axion: PRECISION MEDICINE – EXTINGUISHING THE FIRE OF THE BURNING MAN
“Man on Fire” syndrome, also known as Inherited Erythromelalgia (IEM), is a chronic pain syndrome characterized by burning pain in the hands and feet. The chronic pain of most patients with IEM cannot be relieved by common pain killers making this disease a major unmet medical need.
Precision Medicine is an approach that tailors the prescribed medical treatment to the individual’s genetic makeup. In this Coffee Break Webinar, Dr Yang Yang (Purdue University) discusses advances in the treatment of IEM using a pharmacogenomic approach. The drug responsiveness of different genetic mutations associated with IEM were probed in an in vitro Maestro MEA assay, with the results helping to predict the effective treatment of these IEM patients in the clinic.
This precision medicine approach, guided by genomic analysis and functional profiling, provides a promising new way to extinguish the fire of the burning man.