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Waters: Processing and Interpreting LC/Time-of-Flight MS Data
Mass spectrometry (MS) is becoming more and more common in the day-to-day work of analytical scientists either as a supplement to, or enhancement of, UV and other optical-based measurements. The additional information provided by mass spectrometry is of value in a variety of assays across multiple application areas. For example, Time-of-Flight (TOF) mass spectrometry provides accurate mass measurement for compound confirmation or identification of unknown species. It can also provide enhanced specificity over traditional MSMS techniques in quantitative assays.
In this series of webinars, we will review the concepts of Time-of-Flight (TOF) mass spectrometry. The first seminar of the series will focus on the basic principles of TOF-MS and a comparison with other mass spectrometric techniques. This will be followed by a discussion of the considerations for coupling ESI-MS to liquid chromatography, including MS-compatible mobile phases. The final webinar will review how to process and interpret the resulting data for both traditional small molecule applications and biopharmaceutical applications. Throughout the webinar series, practical examples and tips will be shared so that new users of the technique will gain insights that can be put to immediate use.
Presenter
Michael Daly
Senior Principal Field Applications Specialist
Waters Corporation