Optimization of culture conditions and evaluation of cell health Watch Recording On Demand A major limitation in studying human diseases affecting the nervous system is the ability to culture, monitor and analyze neuronal cells that accurately represent human phenotypes of these disorders. The use of human induced pluripotent stem cell (hiPSC)-derived neurons has provided a […]
HORIBA Instruments and Microfluidics present a seminar on the newest breakthroughs in nanoparticle measurements Wednesday, May 23rd, 2018 Holiday Inn Gaithersburg 2 Montgomery Village Ave Gaithersburg MD 20879 301-948-8900 Marinella Sandros, Ph. D., Horiba Scientific will present "Designed Nano-Bio interfaces using Surface Plasmon Resonance imaging for Biomedical Application." New Technology for the Formulation and Characterization of Mono […]
The increasing importance of large molecule therapeutics has been coupled with advancements in LC–MS technology, opening up new opportunities. Typically, large molecules are analyzed using ligand-binding assays but with advanced progress in MS technology the community has seen increased success in overall sensitivity and selectivity. However, what does this mean for future analysis and what […]
“Man on Fire” syndrome, also known as Inherited Erythromelalgia (IEM), is a chronic pain syndrome characterized by burning pain in the hands and feet. The chronic pain of most patients with IEM cannot be relieved by common pain killers making this disease a major unmet medical need. Precision Medicine is an approach that tailors the […]
Measurement of these metabolites represents the digital readout of health. A key aspect of metabolomics is the utilization of high resolution mass spectrometric approaches to detect and identify metabolites from biological fluids and tissues. The use of multi-analyte analyses as well as high resolution mass spectrometric approaches has the potential to transform clinical diagnostics for […]
Three-dimensional (3D) cell aggregates are of great interest for many applications, including disease modeling, drug toxicity assessment, and manufacture of stem cell-based products. Stirred-tank bioreactors are promising culture systems for 3D cell aggregates, as they allow efficient establishment and maintenance of cell aggregates, process monitoring and control, and process scale-up to larger volumes. Furthermore, they […]
In our daily lives we are exposed to thousands of commercially used chemicals. Many of these chemicals are not toxic at typical exposure levels, but for thousands of chemicals, toxicological information is lacking. The National Academy of Sciences report on ‘‘Toxicity testing in the 21st century’’ highlighted the need for efficient methods to screen chemicals […]
MicroRNAs (miRNAs), small non-coding RNAs that regulate gene expression, hold incredible promise as minimally invasive biomarkers for use in the diagnosis and prognosis of a wide range of diseases and biological processes. miRNAs are transported in body fluids within exosomes, thus making them ideal biomarkers due to their stability and the ease with which they […]
Do you have questions about PCR? Our Technical Support Scientists Natascha Buter and Joliene Lindholm will be answering all your questions about nucleic acid amplification. Learn more about endpoint PCR and how to make sure you have a successful run every time. Register and submit your questions by August 17 to have the best shot […]
Our new cell-by-cell analysis module allows users to ‘count and classify’ heterogeneity in cell populations over time. This software uses novel algorithms to segment the HD phase-contrast images which facilitates (1) label-free true cell counting (2) extraction of basic morphological features of individual cells (e.g. size, shape), and (3) measurement of fluorescence intensity that originates […]